Sam Hajaliloo Sami MD1, Tahmineh Mokhtari PhD2, Gholamreza Shafiee MD3*
1 Iran University of Medical Sciences, Tehran, Iran
2 Tehran University of Medical sciences, Tehran, Iran
3 Golestan University of Medical Sciences, Kalaleh, Iran
* Corresponding Author
Introduction: Benign and malignant soft tissue neoplastic lesions are observed in extremities of children. These tumors have different clinical and epidemiological characteristics. The aim of this study was to evaluate the epidemiological characteristics of childhood soft tissue tumors in extremities in Iranian population.
Materials and methods: In a cross-sectional study, 69 cases (0-16 year old children) were evaluated for benign and malignant soft tissue tumors in their extremities referred to Shafa Orthopedic Hospital, from 2006 to 2012. The pathologic specimens were obtained and the pathologic reports were recorded for each case.
Results: Of all 69 patients with mean age of 12.1±3.1 years at the time of surgery, 30 (43.4%) were female and 39 (56.5%) were male. Pathologic reports of 76.8% of cases were benign lesion and 25.2% were malignant. Most of the lesions (37.68%) were in the hand, after that the most involved region was thigh (20.28%). Hemangioma was the most observed lesion of soft tissue tumors (23.18%) even after rhabdomyosarcoma. The recurrence of tumor was reported in 13 cases with rhabdomyosarcoma.
Conclusion: According to the results, hemangioma was the most observed childhood soft tissue tumors as a benign mass and rhabdomyosarcoma was the most observed as a malignant mass in Iranian population.
Keywords: Soft tissue neoplasms, Sarcoma, Childhood, Iranian population, Orthopaedics, A.12, A.13